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Symbol Name ID |
St14
suppression of tumorigenicity 14 (colon carcinoma) MGI:1338881 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Blepharitis |
| Disease(s) Associated with ST14 | |
| autosomal recessive congenital ichthyosis 11 |
| Mouse Phenotypes | immune system phenotype |
increased thymocyte apoptosis |
colitis |
submandibular gland inflammation |
lacrimal gland inflammation |
decreased double-positive T cell number |
decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number |
increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number |
increased effector memory CD4-positive, alpha-beta T cell number |
decreased CD4-positive, alpha-beta T cell number |
increased effector memory CD8-positive, alpha-beta T cell number |
decreased CD8-positive, alpha-beta T cell number |
decreased regulatory T cell number |
abnormal cytokine secretion |
abnormal chemokine secretion |
increased autoantibody level |
increased anti-nuclear antigen antibody level |
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| Availability | Mouse Genotype | |||||||||||||||||
| St14tm1Bug/St14tm1Bug | ||||||||||||||||||
| St14tm3Bug/St14tm3Bug (conditional) | * | |||||||||||||||||
| St14tm2Bug/St14tm3Bug Tg(Vil1-cre)997Gum/0 (conditional) |
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| St14tm2Bug/St14tm3Bug Tg(MMTV-cre)4Mam/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/07/2024 MGI 6.23 |
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